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Tirzepatide is the next generation in GLP weight loss medications and the results are nothing short of amazing!
Tirzepatide, also known as Mounjaro, is once-weekly injectable dual glucagon-like peptide 1 (GLP-1) receptor and glucose-dependent insulinotropic polypeptide (GIP) receptor agonist. It works by increasing insulin production and lowers glucagon secretion as well as targets areas in the brain that regulate appetite and food intake. A small change in the molecule allows the drug to last weeks in our bodies rather than the natural version our bodies make, which lasts minutes. Tirzepatide does not currently have an FDA designation for weight loss and therefor is being used “off label”.
Tirzepatide acts in the following ways:
● Delays how quickly our stomachs digest food. Leading to a feeling of fullness and satisfaction with smaller meal sizes.
● Slows intestinal motility so you will feel fuller longer after meals.
● Dual action receptor allows for lower blood sugars, in part by reducing the production of sugar in the liver.
● Stimulates insulin secretion by the pancreas.
● GIP increases energy expenditure, resulting in weight loss reductions.
Tirzepatide is given similar to Semaglutide. We will supply you with pre-filled syringes. Our Tirzepatide also contains B12 in each dose that has been shown to help alleviate nausea that can be associated with these types of medications. There is no need to measure your medication as it is ready to go when we give it to you! The injection needs to be given on the same day each week and can be taken with or without food. Tirzepatide is typically given in your abdomen, upper arm, or thigh. It is recommended to change injection sites with each dose.
Possible side effects: Nausea, diarrhea, vomiting, constipation, abdominal pain, headache, fatigue, dyspepsia, dizziness, abdominal distension, belching, hypoglycemia, flatulence, gastroenteritis, and gastroesophageal reflux disease.
A very serious allergic reaction to this drug is rare but can be deadly. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing. Report adverse side effects to your doctor or pharmacist. In the event of any emergency, call 911 immediately.
The most common side effects include nausea and constipation. * Patients also report acid reflux, stomach pain, vomiting, and diarrhea. The risk of serious side effects increases in patients with hypoglycemia, kidney problems, and risk of allergic reactions.
*500mcg/mL of Cyanocobalamin added to reduce nausea side effects.
Tirzepatide can NOT be given to any patient with a history of thyroid cancer or family history of thyroid cancer or a history of MEN 2 or a family history of MEN 2.
Nausea is one of the most common side effects of tirzepatide. If you start experiencing nausea, we recommend trying some ginger chews and ginger ale. There are also many over the counter anti-nausea aids that might help.
You can also give yourself the injection at night before you go to sleep, that may reduce the side effects.
Our goal, at Revive Medical, is to limit these side-effects with a commonsense approach to tirzepatide. Generally, for your first month, we will start you at a lower dose of tirzepatide to allow your body to get used to it and then increase the dose, if needed monthly. The goal is for you to start losing weight with little to no nausea!
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