GLP - 2 (GLP+GIP) Medications

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GLP-2 medications (GLP/GIP)  are formulated to aid in weight management and enhance metabolic health. This dual-action therapy activates both glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptors, providing a well-rounded approach to supporting weight loss and improving blood sugar regulation.

GLP-2 (GLP-1/GIP) medications help suppress appetite and reduce food cravings, making it easier to achieve and maintain a healthy weight.

GLP-2 therapies have shown impressive results in clinical trials, with some patients losing up to 22.5% of their body weight within 6 to 8 weeks—demonstrating their effectiveness as a weight loss solution.

These medications support overall metabolic health by improving insulin sensitivity, lowering blood sugar levels, and reducing the risk of conditions commonly linked to obesity, such as type 2 diabetes, hypertension, and cardiovascular disease.

Achieving a healthier weight with GLP-2 can alleviate symptoms like fatigue, joint pain, and limited mobility, while also enhancing energy levels and overall quality of life.

Revive Medical collaborates with pharmacies that fully comply with Section 503A/503B of the Federal Food, Drug, and Cosmetic Act. This compliance allows for the compounding of medications like GLP-2 (GLP/GIP) when specific formulations are required—whether they are not commercially available, therapeutically different, or unable to meet the patient's unique needs. These compounded medications may address a variety of patient requirements, such as customized dosing, alternative delivery methods, or sensitivities to standard ingredients.

GLP-2 (GLP/GIP) medications are generally safe when used as prescribed and under the supervision of a healthcare provider. Like any medication, however, they can cause side effects. Common side effects include nausea, vomiting, diarrhea, and constipation. These side effects are usually mild and temporary. In rare cases, more serious issues like severe stomach or kidney problems may occur.

It is important to discuss the potential risks and benefits of GLP-2 (GLP/GIP) medications with your healthcare provider. Be sure to promptly report any side effects or concerns you may experience.

Both GLP-1 and GLP-2 (GLP/GIP) medications are FDA-approved for the treatment of type 2 diabetes and supporting long-term weight management.

However, there are key differences:

• GLP-1 medications are primarily designed to mimic the action of the GLP-1 hormone, which helps control blood sugar levels and support weight loss.
• GLP-2 (GLP/GIP) medications take this a step further by also mimicking the action of glucose-dependent insulinotropic polypeptide (GIP), in addition to GLP-1. Research has shown that the combined effect of both GLP-1 and GIP in GLP-2 (GLP/GIP) medications is more effective for weight loss compared to GLP-1's alone.

*Compounded medications are not considered FDA approved, however the active ingredients in the compounded medications are the same medications that are FDA approved in their commercially available forms. All pharmacies used by Revive Medical are inspected, registered and compliant with FDA compounding requirements. 

• Individuals with Type 2 Diabetes:
  GLP-2 (GLP/GIP) medications work by targeting both GIP and GLP-1 receptors, helping improve glycemic control through enhanced insulin secretion and lowered blood sugar levels. This makes it an effective treatment for individuals seeking better management of type 2 diabetes.
• Those Focused on Weight Management:
  Clinical research has shown that GLP-2 (GLP/GIP) medications can aid in significant weight loss by suppressing appetite and reducing caloric intake, making them a beneficial option for individuals struggling with obesity or weight-related health conditions.
• Individuals with Metabolic Syndrome:
  By addressing hyperglycemia, insulin resistance, and excess weight simultaneously, GLP-2 (GLP/GIP) medications offer comprehensive metabolic support, helping individuals with metabolic syndrome improve their overall health.
• Patients with Cardiovascular Risk Factors:
  The combined benefits of improved blood sugar control and weight loss can reduce cardiovascular risk factors, offering significant advantages to individuals with type 2 diabetes, who are at a higher risk for heart disease.
• Individuals Seeking Comprehensive Metabolic Support:
  For those looking to manage multiple aspects of their metabolic health, including blood sugar control and weight management, GLP-2 (GLP/GIP) medications provide a multifaceted approach that can contribute to long-term wellness.

**Revive medical does not treat Diabetes Type-2 or any other chronic health conditions or diagnosis. 

Yes, although a healthcare professional will review your profile before prescribing GLP-2 (GLP/GIP) medications, it is essential to keep your primary care provider informed. Your primary care doctor, who is familiar with your complete medical history, can ensure you receive personalized, comprehensive care. They can also offer valuable insights into your overall health that may not be captured through our service.

GLP-2 (GLP/GIP) medications may not be appropriate for individuals with certain conditions. The following contraindications prevent its use:

• Personal or family history of medullary thyroid carcinoma (MTC) or multiple endocrine neoplasia syndrome type 2 (MEN-2)
• Current use of another GLP-1 receptor agonist
• Diabetic ketoacidosis
• Known hypersensitivity to GLP-1/GIP + B12 or any components of the injection
• Recent bariatric surgery (within the last six months)
• Pregnancy

Additionally, it is important to inform your healthcare provider if you have or have had:

• Stomach or intestinal disorders
• Pancreatitis
• Kidney disease
• Diabetes-related eye conditions

**Always consult with your doctor to ensure this medication is safe and suitable for you. It is very important that you tell your Revive Medical provider your current and past medical history completely. Do not leave anything out to ensure you receive the safest recommendation. It is very dangerous to leave out medical information and could lead to potentially serious consequences, including death. 

To qualify for our weight loss medication, you must meet the following criteria:

• Age: You must be at least 18 years old.
• Location: You need to reside in, or be physically present in, one of the states where our services are available.
• Medical Necessity: You must demonstrate a need for medical treatment. If necessary, our team can help you obtain recent lab results upon request from your healthcare provider.
• FDA Criteria: You must meet the FDA-approved criteria for weight loss medications, which include:
• .
• Exclusions: You may not be eligible if you have any of the following conditions:
  • Type 1 diabetes
  • A history of chronic pancreatitis or pancreatitis induced by weight loss medications (GLP-1)
  • Severe gastrointestinal (GI) disease
  • Current gallbladder issues (except for those who have had gallbladder removal)
  • Retinal impairment or diabetic retinopathy
  • Recent bariatric surgery
  • Multiple endocrine neoplasia syndrome type 2 (MEN-2)
  • A personal or family history of medullary thyroid cancer
• Pregnancy and Nursing: You should not be pregnant or breastfeeding.

*Your eligibility for the weight loss program will be determined by your healthcare provider at Revive Medical, who may request additional information from you as needed.

*Compounded medications are not considered FDA approved, however the active ingredients in the compounded medications are the same medications that are FDA approved in their commercially available forms. All pharmacies used by Revive Medical are inspected, registered and compliant with FDA compounding requirements.